Postdoc in Deep Mutational Scanning at the Department of Biology

Official occupation: Post doc., naturvidenskab og teknik. Employment conditions: Almindelige vilkår. Employer CVR: 29979812.

Primary career market

Public Sector, Education & Impact (occupation evidence). We are looking for a highly motivated and independent Post Doc to lead a 2-year project focused on Deep Mutational Scanning applied to Intrinsically Disordered Proteins (IDPs) in yeast cells to commence 1 May 2027 or as soon as possible thereafter.

Our research The research group investigates how cells maintain protein homeostasis through the protein quality control (PQC) system and how defects in these pathways contribute to disease and aging. Research activities combine molecular genetics, functional genomics, and advanced high-throughput technologies to dissect the mechanisms governing protein folding, degradation, and cellular stress responses.

A central focus is the development and application of Deep Mutational Scanning (DMS) approaches to systematically characterize the functional consequences of genetic variation in selected IDPs in yeast cells. This will require developing and integrating multiplexed assays to uncover sequence–function relationships and map the cellular pathways that influence variant effects1 …